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Novel Role of ER Stress and Autophagy in Microcystin-LR Induced Apoptosis in Chinese Hamster Ovary Cells

Microcystin-LR (MC-LR) is a ubiquitous peptide that exhibits strong reproductive toxicity, although the mechanistic basis for such toxicity remains largely unknown. The present study was conducted to investigate the mechanisms underlying the adverse effects of exposure to MC-LR in Chinese hamster ov...

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Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Zhang, Shenshen, Liu, Chuanrui, Li, Yang, Imam, Mustapha U., Huang, Hui, Liu, Haohao, Xin, Yongjuan, Zhang, Huizhen
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099254/
https://ncbi.nlm.nih.gov/pubmed/27877136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00527
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