Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis

OBJECTIVE: The zinc-ZIP8-MTF1 axis induces metallothionein (MT) expression and is a catabolic regulator of experimental osteoarthritis (OA) in mice. The main aim of the current study was to explore the roles and underlying molecular mechanisms of MTs in OA pathogenesis. METHODS: Experimental OA in m...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Ann Rheum Dis
Päätekijät: Won, Yoonkyung, Shin, Youngnim, Chun, Churl-Hong, Cho, Yongsik, Ha, Chul-Won, Kim, Jin-Hong, Chun, Jang-Soo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Publishing Group 2016
Aiheet:
Basic and Translational Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099198/
https://ncbi.nlm.nih.gov/pubmed/26903440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-208406
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia