Multiparameter Evaluation of the Heterogeneity of Circulating Tumor Cells Using Integrated RNA In Situ Hybridization and Immunocytochemical Analysis

Circulating tumor cells (CTCs) are routinely identified as cytokeratin (CK)-positive, epithelial cell adhesion molecule (EpCAM)-positive, and CD45-negative and are enriched based on EpCAM. However, there are a number of methodological challenges regarding both isolation and characterization of these...

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發表在:Front Oncol
Main Authors: Wu, Yongqi, Park, Kyoung-Joo Jenny, Deighan, Clayton, Amaya, Peter, Miller, Brandon, Pan, Quintin, Zborowski, Maciej, Lustberg, Maryam, Chalmers, Jeffery
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2016
主題:
Oncology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099140/
https://ncbi.nlm.nih.gov/pubmed/27878106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00234
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