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The Design and Analysis of Transposon-Insertion Sequencing Experiments

Transposon-insertion sequencing (TIS) is a powerful approach that can be widely applied to genome-wide definition of loci that are required for growth in diverse conditions. However, experimental design choices and stochastic biological processes can heavily influence the results of TIS experiments...

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Dades bibliogràfiques
Publicat a:Nat Rev Microbiol
Autors principals: Chao, Michael C., Abel, Sören, Davis, Brigid M., Waldor, Matthew K.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099075/
https://ncbi.nlm.nih.gov/pubmed/26775926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro.2015.7
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