Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation.

One approach to gene therapy for hepatic diseases is to remove hepatocytes from an affected individual, genetically alter them in vitro, and reimplant them into a receptive locus. Although returning hepatocytes to the liver itself would be advantageous, the feasibility of this approach has never bee...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ponder, K P, Gupta, S, Leland, F, Darlington, G, Finegold, M, DeMayo, J, Ledley, F D, Chowdhury, J R, Woo, S L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50988/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1899924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.4.1217
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