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Maternal choline supplementation in a sheep model of first trimester binge alcohol fails to protect against brain volume reductions in peripubertal lambs

Fetal alcohol spectrum disorder (FASD) is a leading potentially preventable birth defect. Poor nutrition may contribute to adverse developmental outcomes of prenatal alcohol exposure, and supplementation of essential micronutrients such as choline has shown benefit in rodent models. The sheep model...

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Detalhes bibliográficos
Publicado no:Alcohol
Main Authors: Birch, Sharla M., Lenox, Mark W., Kornegay, Joe N., Paniagua, Beatriz, Styner, Martin A., Goodlett, Charles R., Cudd, Tim A., Washburn, Shannon E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098470/
https://ncbi.nlm.nih.gov/pubmed/27788773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2016.07.004
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