Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow

Disseminated prostate cancer (PCa) cells in the marrow survive for years without evidence of proliferation, while maintaining the capacity to develop into metastatic lesions. These dormant disseminated tumor cells (DTCs) may reside in close proximity to osteoblasts, while expressing high levels of A...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yumoto, Kenji, Eber, Matthew R., Wang, Jingcheng, Cackowski, Frank C., Decker, Ann M., Lee, Eunsohl, Nobre, Ana Rita, Aguirre-Ghiso, Julio A., Jung, Younghun, Taichman, Russell S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098246/
https://ncbi.nlm.nih.gov/pubmed/27819283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36520
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