Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing

Uveal melanoma (UM) is a rare intraocular tumor that, similar to cutaneous melanoma, originates from melanocytes. To gain insights into its genetics, we performed whole-genome sequencing at very deep coverage of tumor-control pairs in 33 samples (24 primary and 9 metastases). Genome-wide, the number...

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Publicat a:Am J Hum Genet
Autors principals: Royer-Bertrand, Beryl, Torsello, Matteo, Rimoldi, Donata, El Zaoui, Ikram, Cisarova, Katarina, Pescini-Gobert, Rosanna, Raynaud, Franck, Zografos, Leonidas, Schalenbourg, Ann, Speiser, Daniel, Nicolas, Michael, Vallat, Laureen, Klein, Robert, Leyvraz, Serge, Ciriello, Giovanni, Riggi, Nicolò, Moulin, Alexandre P., Rivolta, Carlo
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097942/
https://ncbi.nlm.nih.gov/pubmed/27745836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.09.008
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