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Monoclonal antibodies to human butyrylcholinesterase reactive with butyrylcholinesterase in animal plasma

Five mouse anti-human butyrylcholinesterase (BChE) monoclonal antibodies bind tightly to native human BChE with nanomolar dissociation constants. Pairing analysis in the Octet system identified the monoclonal antibodies that bind to overlapping and independent epitopes on human BChE. The nucleotide...

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Publicat a:Chem Biol Interact
Autors principals: Peng, Hong, Brimijoin, Stephen, Hrabovska, Anna, Krejci, Eric, Blake, Thomas A., Johnson, Rudolph C., Masson, Patrick, Lockridge, Oksana
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097833/
https://ncbi.nlm.nih.gov/pubmed/26585590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2015.11.011
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