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Ataxia telangiectasia mutated (ATM) interacts with p400 ATPase for an efficient DNA damage response

BACKGROUND: Ataxia telangiectasia mutated (ATM) and TRRAP proteins belong to the phosphatidylinositol 3-kinase-related kinase family and are involved in DNA damage repair and chromatin remodeling. ATM is a checkpoint kinase that is recruited to sites of DNA double-strand breaks where it phosphorylat...

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Veröffentlicht in:BMC Mol Biol
Hauptverfasser: Smith, Rebecca J., Savoian, Matthew S., Weber, Lauren E., Park, Jeong Hyeon
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097431/
https://ncbi.nlm.nih.gov/pubmed/27814680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-016-0075-7
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