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Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia

INTRODUCTION: In healthy carriers of the T allele of the transcription factor 7-like 2 (TCF7L2), fasting plasma glucagon concentrations are lower compared with those with the C allele. We hypothesised that presence of the T allele is associated with a diminished glucagon response during hypoglycaemi...

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Detalhes bibliográficos
Publicado no:Endocr Connect
Main Authors: Kristensen, Peter L, Pedersen-Bjergaard, Ulrik, Due-Andersen, Rikke, Høi-Hansen, Thomas, Grimmeshave, Lise, Lyssenko, Valeriya, Groop, Leif, Holst, Jens J, Vaag, Allan A, Thorsteinsson, Birger
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097143/
https://ncbi.nlm.nih.gov/pubmed/27758844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-16-0050
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