Cancer-associated fibroblast-derived annexin A6(+) extracellular vesicles support pancreatic cancer aggressiveness

The intratumoral microenvironment, or stroma, is of major importance in the pathobiology of pancreatic ductal adenocarcinoma (PDA), and specific conditions in the stroma may promote increased cancer aggressiveness. We hypothesized that this heterogeneous and evolving compartment drastically influenc...

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Опубликовано в: :J Clin Invest
Главные авторы: Leca, Julie, Martinez, Sébastien, Lac, Sophie, Nigri, Jérémy, Secq, Véronique, Rubis, Marion, Bressy, Christian, Sergé, Arnauld, Lavaut, Marie-Noelle, Dusetti, Nelson, Loncle, Céline, Roques, Julie, Pietrasz, Daniel, Bousquet, Corinne, Garcia, Stéphane, Granjeaud, Samuel, Ouaissi, Mehdi, Bachet, Jean Baptiste, Brun, Christine, Iovanna, Juan L., Zimmermann, Pascale, Vasseur, Sophie, Tomasini, Richard
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096915/
https://ncbi.nlm.nih.gov/pubmed/27701147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87734
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