Similar efficacy from specific and non-specific mineralocorticoid receptor antagonist treatment of muscular dystrophy mice

BACKGROUND: Combined treatment with an angiotensin-converting enzyme inhibitor and a mineralocorticoid receptor (MR) antagonist improved cardiac and skeletal muscle function and pathology in a mouse model of Duchenne muscular dystrophy. MR is present in limb and respiratory skeletal muscles and func...

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Detalhes bibliográficos
Publicado no:J Neuromuscul Dis
Main Authors: Lowe, Jeovanna, Floyd, Kyle T., Rastogi, Neha, Schultz, Eric J., Chadwick, Jessica A., Swager, Sarah A., Zins, Jonathan G., Kadakia, Feni K., Smart, Suzanne, Gomez-Sanchez, Elise P., Gomez-Sanchez, Celso E., Raman, Subha V., Janssen, Paul M. L., Rafael-Fortney, Jill A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096836/
https://ncbi.nlm.nih.gov/pubmed/27822449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JND-160173
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