Aging promotes acquisition of naive-like CD8(+) memory T cell traits and enhanced functionalities

Protective T cell memory is an acquired trait that is contingent upon the preservation of its constituents and therefore vulnerable to the potentially deleterious effects of organismal aging. Here, however, we have found that long-term T cell memory in a natural murine host-pathogen system can subst...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Eberlein, Jens, Davenport, Bennett, Nguyen, Tom, Victorino, Francisco, Haist, Kelsey, Jhun, Kevin, Karimpour-Fard, Anis, Hunter, Lawrence, Kedl, Ross, Clambey, Eric T., Homann, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096808/
https://ncbi.nlm.nih.gov/pubmed/27617858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88546
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