Aging promotes acquisition of naive-like CD8(+) memory T cell traits and enhanced functionalities

Protective T cell memory is an acquired trait that is contingent upon the preservation of its constituents and therefore vulnerable to the potentially deleterious effects of organismal aging. Here, however, we have found that long-term T cell memory in a natural murine host-pathogen system can subst...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Eberlein, Jens, Davenport, Bennett, Nguyen, Tom, Victorino, Francisco, Haist, Kelsey, Jhun, Kevin, Karimpour-Fard, Anis, Hunter, Lawrence, Kedl, Ross, Clambey, Eric T., Homann, Dirk
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096808/
https://ncbi.nlm.nih.gov/pubmed/27617858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88546
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