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A double-blind, randomized, placebo-controlled pilot trial to determine the efficacy and safety of ibudilast, a potential glial attenuator, in chronic migraine

BACKGROUND: Chronic migraine (CM) is problematic, and there are few effective treatments. Recently, it has been hypothesized that glial activation may be a contributor to migraine; therefore, this study investigated whether the potential glial inhibitor, ibudilast, could attenuate CM. METHODS: The s...

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Bibliographic Details
Published in:J Pain Res
Main Authors: Kwok, Yuen H, Swift, James E, Gazerani, Parisa, Rolan, Paul
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096778/
https://ncbi.nlm.nih.gov/pubmed/27826212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S116968
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