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A Novel c.554+5C>T Mutation in the DUOXA2 Gene Combined with p.R885Q Mutation in the DUOX2 Gene Causing Congenital Hypothyroidism

The coexistence of mutations in the dual oxidase maturation factor 2 (DUOXA2) and dual oxidase 2 (DUOX2) genes is rarely identified in congenital hypothyroidism (CH). This study reports a boy with CH due to a novel splice-site mutation in the DUOXA2 gene and a missense mutation in the DUOX2 gene. A...

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Bibliografske podrobnosti
izdano v:J Clin Res Pediatr Endocrinol
Main Authors: Zheng, Xiao, Ma, Shao-Gang, Qiu, Ya-Li, Guo, Man-Li, Shao, Xiao-Juan
Format: Artigo
Jezik:Inglês
Izdano: Galenos Publishing 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096480/
https://ncbi.nlm.nih.gov/pubmed/26758695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/jcrpe.2380
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