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Modular Terpenoid Construction via Catalytic Enantioselective Formation of All-Carbon Quaternary Centers: Total Synthesis of Oridamycin A, Triptoquinone B and C and Isoiresin

Total syntheses of oridamycin A, triptoquinones B and C and isoiresin are accomplished from a common intermediate prepared via iridium catalyzed alcohol C-H tert-(hydroxy)-prenylation; a byproduct-free process that forms an all-carbon quaternary stereocenter with excellent control of diastereo- and...

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Bibliografische gegevens
Gepubliceerd in:J Am Chem Soc
Hoofdauteurs: Feng, Jiajie, Noack, Florian, Krische, Michael J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096378/
https://ncbi.nlm.nih.gov/pubmed/27632643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b08902
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