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The unconventional kinetoplastid kinetochore: from discovery toward functional understanding

The kinetochore is the macromolecular protein complex that drives chromosome segregation in eukaryotes. Its most fundamental function is to connect centromeric DNA to dynamic spindle microtubules. Studies in popular model eukaryotes have shown that centromere protein (CENP)-A is critical for DNA-bin...

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Publicat a:Biochem Soc Trans
Autor principal: Akiyoshi, Bungo
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095916/
https://ncbi.nlm.nih.gov/pubmed/27911702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160112
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