OPN‐a induces muscle inflammation by increasing recruitment and activation of pro‐inflammatory macrophages

NEW FINDINGS: What is the central question of this study? What is the functional relevance of OPN isoform expression in muscle pathology? What is the main finding and its importance? The full‐length human OPN‐a isoform is the most pro‐inflammatory isoform in the muscle microenvironment, acting on ma...

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Pubblicato in:Exp Physiol
Autori principali: Many, Gina M., Yokosaki, Yasuyuki, Uaesoontrachoon, Kitipong, Nghiem, Peter P., Bello, Luca, Dadgar, Sherry, Yin, Ying, Damsker, Jesse M., Cohen, Heather B., Kornegay, Joe N., Bamman, Marcas M., Mosser, David M., Nagaraju, Kanneboyina, Hoffman, Eric P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095808/
https://ncbi.nlm.nih.gov/pubmed/27452303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/EP085768
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