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A self-assembling nanomedicine of conjugated linoleic acid-paclitaxel conjugate (CLA-PTX) with higher drug loading and carrier-free characteristic

The main objective of this study was to demonstrate the proof-of-principle for the hypothesis that conjugated linoleic acid-paclitaxel conjugate (CLA-PTX), a novel fatty acid modified anti-cancer drug conjugate, could self-assemble forming nanoparticles. The results indicated that a novel self-assem...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Zhong, Ting, Yao, Xin, Zhang, Shuang, Guo, Yang, Duan, Xiao-Chuan, Ren, Wei, Dan Huang, Yin, Yi-Fan, Zhang, Xuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095675/
https://ncbi.nlm.nih.gov/pubmed/27812039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36614
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