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Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: K(D) values, binding pairs, and amino acid sequences

Human butyrylcholinesterase (HuBChE) is a stoichiometric bioscavenger of nerve agents and organophosphorus pesticides. Mass spectrometry methods detect stable nerve agent adducts on the active site serine of HuBChE. The first step in sample preparation is immunopurification of HuBChE from plasma. Ou...

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Detalhes bibliográficos
Publicado no:Chem Biol Interact
Main Authors: Peng, Hong, Brimijoin, Stephen, Hrabovska, Anna, Targosova, Katarina, Krejci, Eric, Blake, Thomas A., Johnson, Rudolph C., Masson, Patrick, Lockridge, Oksana
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095618/
https://ncbi.nlm.nih.gov/pubmed/26343001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2015.08.024
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