Determination of an optimally sensitive and specific chemical exchange saturation transfer MRI quantification metric in relevant biological phantoms

The purpose of this study was to develop realistic phantom models of the intracellular environment of metastatic breast tumour and naïve brain, and using these models determine an analysis metric for quantification of CEST MRI data that is sensitive to only labile proton exchange rate and concentrat...

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Publicado en:NMR Biomed
Autores principales: Ray, Kevin J., Larkin, James R., Tee, Yee K., Khrapitchev, Alexandre A., Karunanithy, Gogulan, Barber, Michael, Baldwin, Andrew J., Chappell, Michael A., Sibson, Nicola R.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095597/
https://ncbi.nlm.nih.gov/pubmed/27686882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3614
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