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How EF-Tu can contribute to efficient proofreading of aa-tRNA by the ribosome
It has long been recognized that the thermodynamics of mRNA–tRNA base pairing is insufficient to explain the high fidelity and efficiency of aminoacyl-tRNA (aa-tRNA) selection by the ribosome. To rationalize this apparent inconsistency, Hopfield proposed that the ribosome may improve accuracy by uti...
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| Publicado no: | Nat Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095583/ https://ncbi.nlm.nih.gov/pubmed/27796304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13314 |
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