Glutaminase inhibitor compound 968 inhibits cell proliferation and sensitizes paclitaxel in ovarian cancer

Objective: Our overall goal was to investigate the anti-tumor activity of the glutaminase 1 (GLS1) Inhibitor compound 968 in ovarian cancer cells. The human ovarian cancer cell lines, HEY, SKOV3 and IGROV-1 were used. Cell proliferation was assessed by MTT assay after treatment with compound 968. Ce...

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Publicat a:Am J Transl Res
Autors principals: Yuan, Lingqin, Sheng, Xiugui, Clark, Leslie H, Zhang, Lu, Guo, Hui, Jones, Hannah M, Willson, Adam K, Gehrig, Paola A, Zhou, Chunxiao, Bae-Jump, Victoria L
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095319/
https://ncbi.nlm.nih.gov/pubmed/27830010
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