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The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation
Cross-linkage of the high-affinity immunoglobulin E (IgE) receptor (FcɛRI) on mast cells by antigen ligation has a critical role in the pathology of IgE-dependent allergic disorders, such as anaphylaxis and asthma. Restraint of intracellular signal transduction pathways that promote release of mast...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095291/ https://ncbi.nlm.nih.gov/pubmed/27786273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13198 |
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