A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison's Disease in Humans

CONTEXT: Autoimmune Addison's disease (AAD) is a rare but highly heritable condition. The BACH2 protein plays a crucial role in T lymphocyte maturation, and allelic variation in its gene has been associated with a number of autoimmune conditions. OBJECTIVE: We aimed to determine whether alleles...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Pazderska, Agnieszka, Oftedal, Bergithe E., Napier, Catherine M., Ainsworth, Holly F., Husebye, Eystein S., Cordell, Heather J., Pearce, Simon H. S., Mitchell, Anna L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Special Features
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095240/
https://ncbi.nlm.nih.gov/pubmed/27680876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2016-2368
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