Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids

The development of in vitro culture systems quantitatively and qualitatively recapitulating normal breast biology is key to the understanding of mammary gland biology. Current three-dimensional mammary culture systems have not demonstrated concurrent proliferation and functional differentiation ex v...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Jardé, Thierry, Lloyd-Lewis, Bethan, Thomas, Mairian, Kendrick, Howard, Melchor, Lorenzo, Bougaret, Lauriane, Watson, Peter D., Ewan, Kenneth, Smalley, Matthew J., Dale, Trevor C.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095178/
https://ncbi.nlm.nih.gov/pubmed/27782124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13207
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