GADD45β induction by S-adenosylmethionine inhibits hepatocellular carcinoma cell proliferation during acute ischemia-hypoxia

Growth arrest DNA damage-inducible gene 45β (GADD45β), which influences cell growth, apoptosis and cellular response to DNA damage, is downregulated in hepatocellular carcinoma (HCC). S-adenosylmethionine (SAMe) serves as an essential methyl donor in multiple metabolic pathways and is a polyamine an...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ma, Ding, Shen, Baiyong, Seewoo, Varun, Tong, Hui, Yang, Weiping, Cheng, Xi, Jin, Zhijian, Peng, Chenghong, Qiu, Weihua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095070/
https://ncbi.nlm.nih.gov/pubmed/27177086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9295
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