Paracrine regulation of matrix metalloproteinases contributes to cancer cell invasion by hepatocellular carcinoma-secreted 14-3-3σ

14-3-3σ overexpression results in enhanced hepatocellular carcinoma (HCC) cell migration and HCC tumor vascular-invasion is significantly associated with 14-3-3σ expression. However, increased expression of 14-3-3σ paradoxically suppresses in vitro cell invasion of HCC. We hypothesize that surroundi...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Liu, Chia-Chia, Chang, Tzu-Ching, Lin, Yi-Ting, Yu, Yen-Ling, Ko, Bor-Sheng, Sung, Li-Ying, Liou, Jun-Yang
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095053/
https://ncbi.nlm.nih.gov/pubmed/27175590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9234
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