OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer

Ubiquitination is essential for regulation of cell physiology, protein stability, and signal transduction [1]. Its dysregulation is an important factor in many diseases, including cancer. We explored the potential OTUB1-catalyzed deubiquitination of FOXM1, a transcription factor linked to carcinogen...

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Udgivet i:Oncotarget
Main Authors: Wang, Yiqin, Zhou, Xianrong, Xu, Midie, Weng, Weiwei, Zhang, Qiongyan, Yang, Yusi, Wei, Ping, Du, Xiang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095031/
https://ncbi.nlm.nih.gov/pubmed/27167337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9160
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