Sulfatide interacts with and activates integrin αVβ3 in human hepatocellular carcinoma cells

Integrin αVβ3 is a malignant driver of anchorage-independence and tumor angiogenesis, but its dysregulation in hepatocellular carcinoma (HCC) remains unclear. In this study, we observed that sulfatide significantly promoted integrin αV(ITGAV) expression and wound closure in HCC. We also noted that e...

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Gepubliceerd in:Oncotarget
Hoofdauteurs: Wang, Rong, Qi, Bing, Dong, Yi Wei, Cai, Qian Qian, Deng, Nian Hui, Chen, Qi, Li, Chao, Jin, Yu Tong, Wu, Xing Zhong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095021/
https://ncbi.nlm.nih.gov/pubmed/27145276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9095
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