TP53 mutation variant allele frequency is a potential predictor for clinical outcome of patients with lower-risk myelodysplastic syndromes

TP53 mutations are frequently detected in patients with higher-risk myelodysplastic syndromes (MDS); however, the clinical impact of these mutations on the disease course of patients with lower-risk MDS is unclear. In this study of 154 lower-risk MDS patients, TP53 mutations were identified in 13% o...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Belickova, Monika, Vesela, Jitka, Jonasova, Anna, Pejsova, Barbora, Votavova, Hana, Merkerova, Michaela Dostalova, Zemanova, Zuzana, Brezinova, Jana, Mikulenkova, Dana, Lauermannova, Marie, Valka, Jan, Michalova, Kyra, Neuwirtova, Radana, Cermak, Jaroslav
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094999/
https://ncbi.nlm.nih.gov/pubmed/27167113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9200
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