EZH2-mediated repression of GSK-3β and TP53 promotes Wnt/β-catenin signaling-dependent cell expansion in cervical carcinoma

Enhancer of zeste homolog 2 (EZH2), a catalytic core component of the Polycomb repressive complex 2 (PRC2), stimulates the silencing of target genes through histone H3 lysine 27 trimethylation (H3K27me3). Recent findings have indicated EZH2 is involved in the development and progression of various h...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Chen, Qian, Zheng, Peng-Sheng, Yang, Wen-Ting
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094987/
https://ncbi.nlm.nih.gov/pubmed/27092879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8741
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