Aldehyde dehydrogenase 2 inhibits inflammatory response and regulates atherosclerotic plaque

Previous studies demonstrated that aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism, which eliminates ALDH2 activity down to 1%-6%, is a susceptibility gene for coronary disease. Here we investigated the underlying mechanisms based on our prior clinical and experimental studies. Male apoE−/− mice...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Pan, Chang, Xing, Jun-hui, Zhang, Cheng, Zhang, Ying-mei, Zhang, Lue-tao, Wei, Shu-jian, Zhang, Ming-xiang, Wang, Xu-ping, Yuan, Qiu-huan, Xue, Li, Wang, Jia-li, Cui, Zhao-qiang, Zhang, Yun, Xu, Feng, Chen, Yu-guo
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper: Pathology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094945/
https://ncbi.nlm.nih.gov/pubmed/27191745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9384
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