Deficiency of myeloid-related proteins 8 and 14 (Mrp8/Mrp14) does not block inflammaging but prevents steatosis

The Mrp8 and Mrp14 proteins (calprotectin) accumulate within tissues during aging and may contribute to chronic inflammation. To address this possibility, we evaluated female calprotectin-deficient Mrp14-KO and wild-type (WT) mice at 5 and 24 months of age. However, there was no evidence that age-re...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Swindell, William R., Xing, Xianying, Fritz, Yi, Diaconu, Doina, Simon, Daniel I., Ward, Nicole L., Gudjonsson, Johann E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Gerotarget (Focus on Aging)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094943/
https://ncbi.nlm.nih.gov/pubmed/27224926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9550
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