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Calcium Binding and Disulfide Bonds Regulate the Stability of Secretagogin towards Thermal and Urea Denaturation

Secretagogin is a calcium-sensor protein with six EF-hands. It is widely expressed in neurons and neuro-endocrine cells of a broad range of vertebrates including mammals, fishes and amphibia. The protein plays a role in secretion and interacts with several vesicle-associated proteins. In this work,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sanagavarapu, Kalyani, Weiffert, Tanja, Ní Mhurchú, Niamh, O’Connell, David, Linse, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094748/
https://ncbi.nlm.nih.gov/pubmed/27812162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165709
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