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Dynamic Cholesterol-Conditioned Dimerization of the G Protein Coupled Chemokine Receptor Type 4

G protein coupled receptors (GPCRs) allow for the transmission of signals across biological membranes. For a number of GPCRs, this signaling was shown to be coupled to prior dimerization of the receptor. The chemokine receptor type 4 (CXCR4) was reported before to form dimers and their functionality...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Pluhackova, Kristyna, Gahbauer, Stefan, Kranz, Franziska, Wassenaar, Tsjerk A., Böckmann, Rainer A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094716/
https://ncbi.nlm.nih.gov/pubmed/27812115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005169
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