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Melatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic Microglia

Microglia activation and associated inflammatory response play pivotal roles in the pathogenesis of different neurodegenerative diseases including neonatal hypoxic brain injury. Here we show that caspase3 expression was upregulated in activated microglia after hypoxic exposure, and remarkably, the c...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Yao, Linli, Lu, Pengfei, Ling, Eng-Ang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094586/
https://ncbi.nlm.nih.gov/pubmed/27812200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166010
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