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Sterically Demanding Oxidative Amidation of α‐Substituted Malononitriles with Amines Using O(2)
An efficient amidation method between readily available 1,1‐dicyanoalkanes and either chiral or nonchiral amines was realized simply with molecular oxygen and a carbonate base. This oxidative protocol can be applied to both sterically and electronically challenging substrates in a highly chemoselect...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094546/ https://ncbi.nlm.nih.gov/pubmed/27300467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603399 |
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