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Molecular modeling, synthesis, characterization and pharmacological evaluation of benzo[d]oxazole derivatives as non-steroidal anti-inflammatory agents

A series of N-(2-(4-chlorobenzyl)benzo[d]oxazol-5-yl)-3-substituted-propanamide (3a–3n) were synthesized and evaluated for their acute and chronic anti-inflammatory potential. The structure of the compounds was elucidated by elemental and spectral (IR, (1)H NMR and MS) analysis. The synthesized comp...

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Detalhes bibliográficos
Publicado no:Saudi Pharm J
Main Authors: Shakya, Ashok K., Kaur, Avneet, Al-Najjar, Belal O., Naik, Rajashri R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094471/
https://ncbi.nlm.nih.gov/pubmed/27829803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2015.03.018
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