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Homozygous FCGR3A-158F mutation is associated with delayed B-cell depletion following rituximab but with preserved efficacy in a patient with refractory lupus nephritis

Rituximab (RTX), an anti-CD20 monoclonal antibody, has shown promising results in a small group of systemic lupus erythematosus (SLE) patients treated for lupus nephritis (LN). However, such observations were not confirmed in the double-blind LUNAR study. Accordingly, the factors associated with the...

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Detalhes bibliográficos
Publicado no:Clin Kidney J
Main Authors: Seret, Guillaume, Hanrotel, Catherine, Bendaoud, Boutahar, Le Meur, Yannick, Renaudineau, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094396/
https://ncbi.nlm.nih.gov/pubmed/27818754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfs162
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