A systematic ensemble approach to thermodynamic modeling reveals an enhancer’s logic

To understand the relationship between enhancer DNA sequence and quantitative gene expression, thermodynamics-driven mathematical models of transcription are often employed. These “sequence-to-expression” models can describe an incomplete or even incorrect set of regulatory relationships if paramete...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Syst
Egile Nagusiak: Hassan Samee, Md. Abul, Lim, Bomyi, Samper, Núria, Lu, Hang, Rushlow, Christine A., Jiménez, Gerardo, Shvartsman, Stanislav Y., Sinha, Saurabh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094195/
https://ncbi.nlm.nih.gov/pubmed/27136354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2015.12.002
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