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Primary age-related tauopathy and the amyloid cascade hypothesis: the exception that proves the rule?
Extensive data supports the amyloid cascade hypothesis, which states that Alzheimer’s disease (AD) stems from neurotoxic forms of the amyloid-beta (Aβ) peptide. But the poor correlation between Aβ plaques and neurodegeneration/cognitive impairment, the spaciotemporal disparity between Aβ and tau pat...
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| Pubblicato in: | J Neurol Neuromedicine |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5094182/ https://ncbi.nlm.nih.gov/pubmed/27819070 |
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