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Molecular determinants of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum in Nigeria and the regional emergence of dhps 431V

There are few published reports of mutations in dihydropteroate synthetase (dhps) and dihydrofolate reductase (dhfr) genes in P. falciparum populations in Nigeria, but one previous study has recorded a novel dhps mutation at codon 431 among infections imported to the United Kingdom from Nigeria. To...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Oguike, Mary C., Falade, Catherine O., Shu, Elvis, Enato, Izehiuwa G., Watila, Ismaila, Baba, Ebenezer S., Bruce, Jane, Webster, Jayne, Hamade, Prudence, Meek, Sylvia, Chandramohan, Daniel, Sutherland, Colin J., Warhurst, David, Roper, Cally
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5094156/
https://ncbi.nlm.nih.gov/pubmed/27821281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2016.08.004
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