Stability of methylation markers in head and neck squamous cell carcinomas

BACKGROUND: As cancer progresses, methylation patterns change to promote the tumorigenic phenotype. However, stability of methylation markers over time and the extent that biopsy samples are representative of larger tumor specimens are unknown. This information is critical for clinical use of such b...

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Veröffentlicht in:Head Neck
Hauptverfasser: Virani, S, Light, E, Peterson, LA, Sartor, MA, Taylor, JMG, McHugh, JB, Wolf, GT, Rozek, LS
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093769/
https://ncbi.nlm.nih.gov/pubmed/26566081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.24223
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