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SSA-ME Detection of cancer driver genes using mutual exclusivity by small subnetwork analysis
Because of its clonal evolution a tumor rarely contains multiple genomic alterations in the same pathway as disrupting the pathway by one gene often is sufficient to confer the complete fitness advantage. As a result, many cancer driver genes display mutual exclusivity across tumors. However, search...
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| Udgivet i: | Sci Rep |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5093737/ https://ncbi.nlm.nih.gov/pubmed/27808240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36257 |
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