Functional variants of the 5-methyltetrahydrofolate-homocysteine methyltransferase gene significantly increase susceptibility to prostate cancer: Results from an ethnic Han Chinese population

Aberrant DNA methylation has been implicated in prostate carcinogenesis. The one-carbon metabolism pathway and related metabolites determine cellular DNA methylation and thus is thought to play a pivotal role in PCa occurrence. This study aimed to investigate the contribution of genetic variants in...

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Publicado en:Sci Rep
Autores principales: Qu, Yuan-Yuan, Zhou, Shu-Xian, Zhang, Xuan, Zhao, Rui, Gu, Cheng-Yuan, Chang, Kun, Yang, Xiao-Qun, Gan, Hua-Lei, Dai, Bo, Zhang, Hai-Liang, Shi, Guo-Hai, Zhu, Yao, Ye, Ding-Wei, Zhao, Jian-Yuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093691/
https://ncbi.nlm.nih.gov/pubmed/27808252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36264
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