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Bioinspired seeding of biomaterials using three dimensional microtissues induces chondrogenic stem cell differentiation and cartilage formation under growth factor free conditions

Cell laden biomaterials are archetypically seeded with individual cells and steered into the desired behavior using exogenous stimuli to control growth and differentiation. In contrast, direct cell-cell contact is instructive and even essential for natural tissue formation. Namely, microaggregation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leijten, J., Teixeira, L. S. Moreira, Bolander, J., Ji, W., Vanspauwen, B., Lammertyn, J., Schrooten, J., Luyten, F. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093556/
https://ncbi.nlm.nih.gov/pubmed/27808102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36011
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