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Novel SCC mutation in a patient of Mexican descent with sex reversal, salt-losing crisis and adrenal failure

Congenital adrenal hyperplasia (CAH) is caused by mutations in cytochrome P450 side chain cleavage enzyme (CYP11A1 and old name, SCC). Errors in cholesterol side chain cleavage by the mitochondrial resident CYP11A1 results in an inadequate amount of pregnenolone production. This study was performed...

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Detalhes bibliográficos
Publicado no:Endocrinol Diabetes Metab Case Rep
Main Authors: Kaur, Jasmeet, Rice, Alan M, O’Connor, Elizabeth, Piya, Anil, Buckler, Bradley, Bose, Himangshu S
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093401/
https://ncbi.nlm.nih.gov/pubmed/27855232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EDM-16-0059
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