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Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Thousands of long non-coding RNAs (lncRNAs) lie interspersed with coding genes across the genome, and a small subset has been implicated as downstream effectors in oncogenic pathways. Here we make use of transcriptome and exome sequencing data from thousands of tumours across 19 cancer types, to ide...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ashouri, Arghavan, Sayin, Volkan I., Van den Eynden, Jimmy, Singh, Simranjit X., Papagiannakopoulos, Thales, Larsson, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093340/
https://ncbi.nlm.nih.gov/pubmed/28959951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13197
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