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Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Thousands of long non-coding RNAs (lncRNAs) lie interspersed with coding genes across the genome, and a small subset has been implicated as downstream effectors in oncogenic pathways. Here we make use of transcriptome and exome sequencing data from thousands of tumours across 19 cancer types, to ide...

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Vydáno v:Nat Commun
Hlavní autoři: Ashouri, Arghavan, Sayin, Volkan I., Van den Eynden, Jimmy, Singh, Simranjit X., Papagiannakopoulos, Thales, Larsson, Erik
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093340/
https://ncbi.nlm.nih.gov/pubmed/28959951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13197
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